AstraZeneca Restructuring

New CEO to announce outcome of new restructuring plan in Jan Feb, what's he going to say?

http://www.nytimes.com/2013/0

http://www.nytimes.com/2013/03/21/business/astrazeneca-to-pay-240-millio...

"Middle management appeared

"Middle management appeared to be obsesed with doing everything according to the correct procedure, which involved a multitude of boring meetings with people who there was really no rationale to involve..."
Same when I was with O-CD. My US manager more concerned with the process of running the meeting (and scoring it for various irrelavent critiria) than the outcome.
Where are the new products, guys?

All quiet at Macc?

All quiet at Macc?

Don’t fool yourself. I came

Don’t fool yourself.

I came to the UK 15 years ago - the UK, land of milk and honey, paradise island, Oxbridge, the city, a new economy, no more boom and bust, house prices always go up, the new Jerusalem, bla bla.

So, what’s left?

Traditional drug R&D

Traditional drug R&D certainly gone fron UK for, what, 10 years. AP will be running on empty untilb it closes, slowly leaking its staff away and the new site will take years to fully build, staff & establish any sort of project portfolio. For several years projects will be old favorites of new staff from past company or academic interests.

Boston, Bay Area, Basel left

Boston, Bay Area, Basel left over.

R+D in UK: gone.

R+D in UK: gone.

Stevenage peterborough

Stevenage peterborough saffron Walden ely. Buntingford. Hitchin letchworth. .........

I know McMillan well, he bust

I know McMillan well, he bust a gut with Charnwood and was truly shocked at the closure. He did not bugger off to a new life somewhere he still lifes in the same house in Macclesfield.

Brennan promised to visit Chw

Brennan promised to visit Chw during closure - took him about 18 months to show up.
McMillan blundered his closure presentation, promised to help everyone then cleared off to a new life before long.

MITP, Leadership

MITP, Leadership Capabilities, Lean Sigma, Knower/Learner etc ..

I was with AZ for 15 years. In my humble opinion all the initiatives above were sound if people had/took time to understand and learn from them.

AstraZeneca's issue is that it has a leadership problem and I don't necessarily mean at the top I mean in middle management and these initiatives were put in to solve it. Unfortunately these so called leaders were too blind to see that it was aimed at them and not the soldiers so they have blundered on ruining what was once a great company seeking out more and more comfortable positions as was said earlier. In all my years at AZ the boys in the leadership team that I worked under were for ever just restructuring themselves and even when they got chucked out they miraculously appeared somewhere else forming their next empire. And lastly "diversity" someone better explain to them what it means before they pop another clone out the bag.

I loved the company and the people but could foresee the future, no business can survive working the way AstraZeneca does .. they really need to take a good look at all these hangers on and get rid of them instead of the hangers on ruling the company.

CVGI in Molndal cut by 1/3

CVGI in Molndal cut by 1/3 (100 FTEs).

Same at Chw after closure

Same at Chw after closure announcement and then Pharm Dev reorganisation. It was rank and file free fall for many, many months.

I left AP in 2008. When I was

I left AP in 2008. When I was there there were a lot of senior managers making roles up to justify their existence - value chain leader, process improvement, lean sigma etc. These people seemed to just want to push their own agendas and play at politics. As soon as the redundancy announcements came they went into self preservation mode and left the staff high and dry until they had sorted out comfortable positions for themselves. They need to take a look at themselves.

Brennan didn't deliver the

Brennan didn't deliver the blow at Charnwood either. McMillan did, and was very humble in his delivery.

I've been to AP about ten

I've been to AP about ten times, and every time I was struck by how empty the labs were and how many that were loitering in the offices. Middle management appeared to be obsesed with doing everything according to the correct procedure, which involved a multitude of boring meetings with people who there was really no rationale to involve...

I thought he was at AP. If,

I thought he was at AP. If, in fact, he was not, it says a lot about his interpretation of "accountability".

"Trying to get a fix on this

"Trying to get a fix on this soriot character.
Faced with which site to visit for this communication he chose to whoop it up with his biological friends in cambridge - an easy crowd. Rather than deliver the hard news to a site he alone decided to close.
Tells you all you need to know about him. Primates eating Camembert waving white flags springs to mind."

+1

First hard decision and he totally ducks out of the pain, not even going to a site with small cuts, leaving it to his minions. First test, first major fail. Even Brennan faced up to the cuts he made.

Good luck to all left at AZ under this "brave" new leadership.

You should change this to AP

You should change this to AP and not AZ. Having worked on three AZ R&D sites I was shocked at the difference between AP and the rest. After 5 years at AP a move to the US was so positive. Much less review, flat politics, positive supportive colleagues and much more autonomy made this place a joy to work in. I had a very similar experience in Sweden. It was like a different company. If MP & PS have witnessed this vast difference I don’t blame them for closing Alderley. It's sad to say but a small, very vocal population of individuals from all levels in the organization has ruined a great site for the 90% of amazing and talented people who truly gave a shit about what they were doing for science and AZ. I now work for Novartis and am enjoying more of the same. I genuinely wish all Cambridge movers the greatest of success. Not just for you personally but for AZ and the UK economy.

Structure certainly sucks. AP

Structure certainly sucks.
AP has team leaders, associate principle scientist (APS) designers, APS managers, APS synthetic chemists and syn chems. Simplified structure?
Thank you LH.

The hopeless project

The hopeless project structure isn't AP specific, you Brits forced it upon the Swedish organisations as well. So, with AP gone the legacy will live on in Molndal. Thanks a lot.

I was not impressed by mene's

I was not impressed by mene's performance on 'north west tonight'. It looked like being read from a script, so that's a 'partially met' in az terminology.
I agree with all the comments in the threads below about the az performance management system. This was a US HR driven system that may have been ok for the USA but was rubbish for the Brits & sweds. It was almost designed to demotivate people & if anyone pointed out that it did not actually achieve higher performance, it was a career limiting comment & they were looked on as unreformed dinosaurs. HR needs to become a support function & not a dominant function. It's r&d that drives new products, not HR !
Having said all that, I think the AP people have got a bum deal out of this & it's hard to understand how Mondal have got away with it yet again.

Trying to get a fix on this

Trying to get a fix on this soriot character.
Faced with which site to visit for this communication he chose to whoop it up with his biological friends in cambridge - an easy crowd. Rather than deliver the hard news to a site he alone decided to close.
Tells you all you need to know about him. Primates eating Camembert waving white flags springs to mind.

You should have grown a

You should have grown a backbone instead

Came to AZ with enthusiasm

Came to AZ with enthusiasm and an open mind and all the bull s--t took care of that.

Yeah,'cos the medi guys in

Yeah,'cos the medi guys in cambridge aren't cynical and embittered at all. They're all singing zippidy do dah out of their ass holes

Worker bees - all behaving

Worker bees - all behaving identically to a pre-defined schedule was exactly what AZ wanted. Scientist complained because they were innovative individuals with opinions and skills that were supressed. Net result projets all ran to a defined, flawed pattern. New-AZ needs to put research back in the hands, hearts and minds of its grass roots scientists.

This thread is just

This thread is just incredibly boring. Please don't post threads like this.

I can concur with the post

I can concur with the post below:

The rot set it once project teams were dis-empowered to undertake the work that they thought would progress compounds.
These team typically consist of 15+ PhD/Degree/MD level scientists, they react to data by discussing the next experiments that need doing to move forwards understanding. However, to proceed each functional rep must take the experiment plan back to their home functions for peer review, meaning that management and other scientists not connected with the project have the power of veto on progression.

Therefore to avoid this project scientists pre-test their ideas in review before going to project teams. This does not however negate the function review once a plan is firmed up by the team. It still happens and plans are modified again, which means its back to the project team to discuss again.

now when you add in the technical resource management having their 2 peneth to discuss if its worthy of doing you can get anywhere up to 5 reviews prior to getting a simple efficacy/safety/DMPK study being done.

This is stressful and sucks the scientific life out of an individual. People start to figure out the path of least resistance, and so start briefing so called "key players" off line to get their support prior to each review. This results in increasing the number of discussing about a simple piece of work.

Project scientists at AZ become embittered United Nation style diplomats to keep everyone happy.

the performance review system is such in AZ that making anyone of the Review teams unhappy will result in a down graded performance review to Unmet (previously termed partially met.

Life in AZ was and still is a merry go round of endless discussions, peer review and removal of the power to just go a do stuff

Innovation is the supposed buzz word -but in reality if it ran starkers round the site no one would see it.

Management instilled this culture of endless review, demanded it. People give up fighting against it once your career/bonus and happiness hit the buffers due to you speaking out.

major change in the top brass folk that run the place is needed. i have lots of friends caught up in this mental working spiral of insanity, it makes many of them ill and now they drop this bomb on them.

I no longer work there, but

I no longer work there, but here is a true story.

Two possible scenarios were discussed for how to organise work at AP.

1. Request comes in, team leader on own judgement decides if he has resource, allocates to a scientist who does work, writes and interprets report,no further management needed.

2. Request comes in. In order to ensure that we are delivering value,and - god forbid - doing an experiment that we might not know the result of before doing it - a process involving about ten different decision points and handovers is devised. All work has to be pre-approved by stakeholder management to ensure alignment to value chain, objectives and portfolio; scientists are not allowed to interpret own data (there is a process for that), actual work is done by unempowered technicians with an embittered PhD supervisor. Reports have to be signed off by dept head + section head + statistician, by another process.

Can you guess which is how AP set it all up?

Thanks for the feedback Mene

Thanks for the feedback Mene

employees who leave their

employees who leave their negativity behind at AP and come down to Cambridge with enthusiasm and an open mind will do very well and maybe AZ can prosper

I suggest anyone considering

I suggest anyone considering relocating to cambridge buys a mobile home cuz you can guarentee that within a year of moving there will be yet another new strategy for success.

Oh, I made things happen

Oh, I made things happen alright.
Still do, but just not there.

And never at AP.

see below for definition of

see below for definition of Bull S#*T

MITP, Leadership

MITP, Leadership Capabilities, Lean Sigma, Knower/Learner etc.
RESULT of the above:
Everyone wants to be a leader and no one wants to do any proper scientific work. The offices are full of people having meetings to discuss what do to and the labs are empty.the labs only come to life when there are visitors coming.

Worker bees moaning about

Worker bees moaning about senior management.....yawn.
Maybe you should have listened at those learner player workshops and made things happen.
It's people being so negative and relentlessly wise after the event that created the atmosphere at AP which Mene and PS so disliked.

100% correct!!!

How do you know what Mene or

How do you know what Mene or S disliked so much?

Worker bees moaning about

Worker bees moaning about senior management.....yawn.
Maybe you should have listened at those learner player workshops and made things happen.
It's people being so negative and relentlessly wise after the event that created the atmosphere at AP which Mene and PS so disliked.

MITP, Leadership

MITP, Leadership Capabilities, Lean Sigma, Knower/Learner etc.

So glad I got away.

MONORAIL!

MONORAIL!

Dont you get it! Not many

Dont you get it! Not many Northerners are going to be allowed to move...

Under a Tory government

Under a Tory government northerners generally have to get on a bike. Cambridge has lots of bikes to make them feel at home.

Worked at AP until last June.

Worked at AP until last June. Look at what wonderful initiatives like Leadership Capabilities, Continuous Improvement and metrics have helped to achieve. Shame senior management couldn't see the light of day and let scientists do their job as they know how then maybe drugs would have been discovered. Has been going wrong since the company cock ups over Exanta and Irresa. All of the serious errors at senior management levels. Always the company workers who carry the can and suffer most in the end. AZ now reaping the rewards of those errors.

Sites under consideration are

Sites under consideration are adjacent to Francis Crick Avenue and Newmarket Road areas.

Agree completely, a merger

Agree completely, a merger within the year will stop all the building plans.

The whole ball game with AZ

The whole ball game with AZ is growth of Brillinta.
As a result I predict AZ will never set foot in CAmbridge.

Pascal has completely failed after only months in the job. This was the last hope - game over.

Cambridge UK site to be next

Cambridge UK site to be next to Addenbrooks Hospital

100 from CVGI? Does it mean

100 from CVGI? Does it mean leaving some areas of research or are all areas to cut about 30%?

"That, my boy, is the whole

"That, my boy, is the whole point. There's no desire to see even 50% transfer. That would then be 'same shit, different postcode'. Not what your man wants".

You are right on the money - when are folks at AP going to realise it is 1600 roles not people that are being relocated. It is not whether even 50% are prepared to relocate, Pangalos et al want much much less than 50% to relocate. Soirot and Pangalos want rid of AP and the staff therein. They will try to keep a small number of key individuals which each function will have to identify, the rest will be out. The reality is come 2016, the majority of people currently employed by AZ at Alderley Park will be no longer employed by AZ. The purpose of the new base in Cambridge is to clear the decks and start again. Sad but true.

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