AstraZeneca Restructuring

New CEO to announce outcome of new restructuring plan in Jan Feb, what's he going to say?

"Sales of Mr Muscle will

"Sales of Mr Muscle will ........."

Oh lovely days spent with a bucket of Mr. Muscle and a mop cleaning out a fume-cupboard - first with acetone, then ethanol, then water.

Oops did I give away some AZ know-how??

So much fun - the end to a career.... no clock or retirement do.

No. Astra should move to

No. Astra should move to Milton Keynes and do what Glaxo have done, but offer labspace at competitive rates. This way they can be near oxford and cambridge.

Another alternative would be to move near colworth where there is an existing science park.

Moving to cambridge just to blend in is pointless. Just buy a couple more biotechs and work more closely with them instead of via webex.

A plot will be bought, but no

A plot will be bought, but no construction will ever take place. Expiring patents/free-falling revenue will see to that.
There will be a u-turn in the face of lost profits, and a now-idle (but interestingly still intact) site - ideally sized - will rise, phoenix-like, from the flood-plains.

... So, has the decision been

... So, has the decision been made yet on the site for the new Cambridge setup? What are the rumours?

Yes but can you get

Yes but can you get broadband?
Do you have a phone line?
Are the red cross dropping packages from above as soon as a snowflake appears.
Live out west near st neots is best but the a14 is a death trap.

"You have just proved why

"You have just proved why they are moving because you don't LISTEN because you thought you were the best of the best.Now you are joining the rest"

Who said I work/worked for AZ. Perhaps you should READ the post.

Sales of Mr Muscle will go

Sales of Mr Muscle will go through the roof as highly paid scientists will hang up their lab coats and exchange these for rubber gloves and set to cleaning, packing and decomissioning labs. Working on projects will be impossible when the labs and equipment fail as the maintenance contracts have been cancelled. It doesn't matter anyway as only guy who knew how to use it has left to start a teacher training course. YourMove becomes the website of choice for idling away time and estate agents are rubbing their hands with glee at all the sales coming their way. This is the future!

Surely R&I will be developed

Surely R&I will be developed as a serious drug discovery unit as PS has stated several to R&I is. Priority disease area.

Fully agree with arrogant so

Fully agree with arrogant so called leaders at AP. I have never understood the work culture there.

Molndal R&I was populated by

Molndal R&I was populated by people who wangled the best deal out of AZ for moving and couldn't think of anything better to do. You sow what you reap. In this case nothing.

Molndal R&I was populated by

Molndal R&I was populated by a random bunch who decided they were willing to go and were then shoehorned into a structural unit as best as possible - never looked like a serious drug discovery unit was being assembled. Cambridge may, if handled right, offer the clean start that AZ need and PS appears to want. But its a long term, risky & expensive venture. Wish them well.

you don't have to SHOUT. The

you don't have to SHOUT. The point you are missing is that the geography of the site and the nature of the people who occupy it are completely independent of one another. Changes could've been made to the staff at AP if that was what was needed without building a whole new site in Cambridge. Moving R&I to Molndal changed very little as it was populated by the same pool of people from Lund and Charnwood.

"the idea that innovative

"the idea that innovative ideas and blockbuster new products are going to permeate through the fabric of the building just by being in Cambridge is also wishful thinking"

You missed the point its not about a building. The building will be full of people who will LISTEN to new ideas.

You have just proved why they are moving because you don't LISTEN because you thought you were the best of the best.Now you are joining the rest.

"the idea that innovative

"the idea that innovative ideas and blockbuster new products are going to permeate through the fabric of the building just by being in Cambridge is also wishful thinking."

Another Pharma moved one of its research units there in 2011, but as far as I can see it is the same business model and people, just at a different location. Judging by their portfolio, Cambridge hasn't sprinkled the promised magic dust on them so far. I wonder how long it will be before their HQ loses interest.

Maybe if AZ take the chance to refresh the leadership, then Cambridge might just work, instead of being viewed cynically as following the crowd. Given that, as has been quoted many times before on this site, "lions led by donkeys" seems a very fitting epitaph for the leadership in big pharma R&D over the last 10-15 years.

the idea that innovative

the idea that innovative ideas and blockbuster new products are going to permeate through the fabric of the building just by being in Cambridge is also wishful thinking.

" The real challnege will be

" The real challnege will be to rebuild the small molecule oncology organisation, which has been relately successful in recent times with Iressa, Faslodex and Vandetinib selling $1.7b in 2012 and growing."

Wishful thinking. Typical AP thinking. Small molecules, particularly in cancer, are toast. They are too dirty, too indiscriminate.

No, you are indulging in mindless optimism. AZ are moving to Cambridge to change the 'game'. To do that they need to be close to where people are thinking creatively and are not wedded to an old and dying paradigm.

Pascal is doing allright. For

Pascal is doing allright.
For him self that is.
He was paid £275,000 and got a hefty £335,000 bonus for his first three months in the job. His annual salary is £1.1m and his annual bonus could be 180% of that.

He also got a £4m “golden hello” to compensate him for the loss of bonuses from his last employer.

So, £4,610,000 for three months work? Not bad, ...or is it?

What has gone wrong with this

What has gone wrong with this company? I left just before Zeneca was born ie I worked for
ICI Pharrmaceuticals. It was a great company. We discovered and marketed lots of great drugs. I find it sad that it has come to this.

Zeneca was what was wrong

Zeneca was what was wrong with AstraZeneca. Bureaucracy, Kepner-Tragoe, etc. Completely stifled free-thinking - as long as you'd based your decisions on objective data crunching, then had several meetings to gain buy-in from the yes-men (because this is the way we've ALWAYS done it), you were fine.

Last week we were told that

Last week we were told that Cambridge would be the heart of the AZ organisation. Despite some scepticism on this board, I do believe that Cambridge will happen. You cannot tell the external world that you plan to create a new hub, and that Oncology is one of the key therapy areas, and not do it. The real challnege will be to rebuild the small molecule oncology organisation, which has been relately successful in recent times with Iressa, Faslodex and Vandetinib selling $1.7b in 2012 and growing.

Personaly I hope it works out - I don't see the value in hoping otherwise.

arrogance and crippling

arrogance and crippling bureaucracy is a pretty good description of Charnwood too. Don't know how many times we were told (by Charnwood management) we were the jewel in the crown of AZ.

I would say that arrogance

I would say that arrogance had spread to larger parts of AP than in most other sites, but among the old guard at Molndal ("we inventerd Losec and should be treated as demi-gods") there was also an attitude that still lingers on. AP, Molndal & Carthage ought all to meet the same destiny...

Having worked at other sites

Having worked at other sites I agree that "arrogance" characterises AP. Stuffed shirts (blouses) and hubris. There was never any willingness to accept other's ideas. I can fully understand why a geographic move is necessary to achieve an innovative research function. Per force this means leaving a large number of the employees behind.

"........may you all get what

"........may you all get what you want"

Or get what you deserve.......... I worked at AP for a while, best thing I did was get away from the place - absolutely bizarre place to work, thankfully I was there only short while, I got out when I could. The arrogance of the people who work there, coupled with the crippling bureaucracy, had to be experienced to be believed. Chickens coming home to roost me thinks....

Well, we await the

Well, we await the consultation period to close to find out if its a quick restructure to the new organisation or a slow death till 2016. Restructuring is going to cause more delays with the development pipeline, personally I will do my job, but why go the extra mile? Those leaving upon being served notice can have 20% of their time job hunting. How is this going to aid Menes productivity?

Don't go to Cambridge, if things go to plan AZ will have a great pipeline, but not enough revenue to defend a takeover. The last restructure was sold to staff as the making it fit for the patent cliff, so can AZ be really trusted on its word. I foresee that 2019, Cambridge site closes, where are you then? You won't have Mene or Pascals severance to fall back on.

As for housing, yes, there are cheaper locations e.g. Haverhill, Duxford and Royston,. But there's going to be a commute with traffic jams and schools that aren't the best. All of this, and stress at a performance driven culture. After all if you move down there, why stay at AZ. After all recently AZ has made a point of not promoting internally, outside is best.

Well good luck to all, may you all get what you want.

Re Debbie at AZ she was moved

Re Debbie at AZ she was moved around to areas they wanted to perform badly so they had a reason for big reorganization or closure.

http://images.yuku.com/image/

http://images.yuku.com/image/jpeg/

6da35b6382eea985026c032430d0851a6858ef5.jpg

Absolute Location: http://images.yuku.com/image/jpeg/6da35b6382eea985026c032430d0851a6858ef...

Don't know what will work here. Tried to join the link together and give again as one link. Hope it works.

Brighton link

Brighton link

And still not spent a penny

And still not spent a penny of the redundancy payment thank you very much.

Couldn't follow your link

Couldn't follow your link re:Brighton - can you re-post the full one for us?

Whoever flagged my post about

Whoever flagged my post about Brighton needs to get a sense of humour. It's the only way to get through it. Been there with AZ and got through it myself.

Welcome to

Welcome to Cambridge

http://www.rightmove.co.uk/property-for-sale/property-26043309.html

Welcome to Hell!

I think I may have something

I think I may have something here. I'm on holiday in Brighton at present and found this management consultant. :)

http://images.yuku.com/image/jpeg/6da35b6382eea985026c032430d0851a6858ef...

Always seemed to get promoted

Always seemed to get promoted to her next level of incompetence before her disastrous legacy was revealed.

Question there is - who hired

Question there is - who hired her into such a position in the first instance? Another example of what was inherently wrong, right there.

"There were a few bad

"There were a few bad managers at AZ but she out classed th all. Utterly clueless and certainly didn't have a track record of drug discovery"

Absolutely right - totally clueless. I remember being in a meeting with senior people from a company with which AZ had a drug discovery alliance. In addition to senior people from AZ (including Jan Lundberg) and the partner, the meeting also included top asthma KOLs from all over the world. During a really interesting discussion about asthma, Dr Hartman, who was VP for Respiratory and Inflammation at AZ Charnwood at the time, leant across and asked 'what is atopy ?' 'nuff said........

There were a few bad managers

There were a few bad managers at AZ but she out classed th all. Utterly clueless and certainly didn't have a track record of drug discovery.

“Debbie has a strong track

“Debbie has a strong track record of .... (fill in the gap)

e.g. totally demoralising everyone.

3 years ago she had 0 years

3 years ago she had 0 years of drug development experience....... Fast worker

That'll be the end of them

That'll be the end of them then.... ;-)

Barbara S. Fox, Ph.D., chief

Barbara S. Fox, Ph.D., chief executive officer of Avaxia, said, “Debbie has a strong track record of delivering new drugs into the clinic and managing early clinical development. "
Really??

Good luck Avaxia - you'll need it!

I think 21:01 refers to

I think 21:01 refers to

AstraZeneca veteran Deborah Hartman joins Avaxia
Will lead the development of AVX-470 in ulcerative colitis
Former AstraZeneca (AZ) vice president Dr Deborah Hartman has joined Avaxia Biologics as VP research, replacing Dan Tracey ......

Some good

Some good news:

http://www.pmlive.com/appointments/research/2013/march/astrazeneca_veter...

For all those that had the pleasure of working with this person.

Brings back some unpleasant memories

An economy in free-fall.

An economy in free-fall. Banks underfunded. Hospital killing people. Our industry in terminal decline.

And British people discussing house prices.

Mene referred to himself as

Mene referred to himself as one of those good scientists that had been atteacted to AP and several hundred annoyed people burst out laughing :oD

Exactly. Mene refused to

Exactly. Mene refused to answer the question 'how may staff do you want to relocate' and just answered 'how many staff he expected to relocate',

Let's not forget the empathy

Let's not forget the empathy Mene showed when announcing the news and his self reference to AZ reecently recruiting 'good scientists'. Still, at least we can all look forward to 'chatting about work with our colleagues' by coffee machines. Worth a move to Cambridge. It was perfcetly feasible and definitely cheaper to develop Alderley Park site even to the extent of putting up new buildings to replace the existing ones. The motive for moving to Cambridge is remove and replace staff at Alderley Park which cannot be done on such a scale without a (ahem..justified) relocation. Pascal has constantly referred to the lack of diversity at Alderley Park .. whatever that refers to. This is how he will achieve it.

This is so funny. Is this

This is so funny. Is this your family house ?

http://www.rightmove.co.uk/s6p/37913258

30 minutes drive is about 5 miles in Cambridge. I agree there are parts of Norfolk that are still cheap and up and coming. The flood defences may be installed by 2016.

In cambridge it may well cost

In cambridge it may well cost £450k for a family house but you clearly know nothing about house prices "in the cambridge area" so please don't put your ridiculous posts up!
I have a large 4 bedroom family house in a very nice area with a big garden and good schools/pubs/shops etc that is within a 30min drive of any part of cambridge you would wish to get to and it cost around £200k...2 bedroom flat indeed...you clearly know nothing!

Assuming you can find a house

Assuming you can find a house in Cambridge area for sale then its going to be a lot more than £200k. £200k is at best a two bed flat. £450k is a family house. Think London prices for anything you would want to live in. When houses come up for sale they are bought up and converted to student houses.

If you have children the house you find may not be near a school you would want them to go to. Cambridge area has one of the highest shortfalls in school places nationally but does have very good schools with the associated big waiting lists.

Then there is the A14 which is one of the busiest roads in the UK. Commuting into Cambridge is very difficult and again comparible with London. The council discourages cars but encourages cycling and buses in the city.

The good news is that its drier and warmer than Manchester.

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