AstraZeneca Restructuring

New CEO to announce outcome of new restructuring plan in Jan Feb, what's he going to say?

It seems better and at least

It seems better and at least optimistic to have a golden hello, far better than DBs golden handshake for doing a disastrous job.

the whole market is up (due

the whole market is up (due to central bank intervention) but AZ is under-performing compared to other healthcare and pharma stocks.

They may lambast the golden

They may lambast the golden hello but the share price is still performing very well. Someone believes he will deliver!!

U.K. funds lambaste

U.K. funds lambaste AstraZeneca CEO's £4M 'golden hello'.

New poster to appear at all

New poster to appear at all AZ sites:
http://www.iamrogue.com/images/stories2/posters/safehouse.jpg

"What will happen to HTS in

"What will happen to HTS in AZ? Will it move to the fantasy new Cambridge site or will it be toast?"

the last 7yrs should tell you that any person, function or site in AZ is potentially toast, noone at AZ should get too comfortable.

In the absence of real news

In the absence of real news people crave any news. I can therefore let you know that HTS is to be established on a site in Leicestershire. Discussions are ongoing to buy the site from a plastics company who are currently maximizing this sites usage by storing bundles of recycling plastic in it's carpark.

What will happen to HTS in

What will happen to HTS in AZ? Will it move to the fantasy new Cambridge site or will it be toast?

What's the favoured site in

What's the favoured site in Cambridge? Granta Park? Babraham?

oncology is not one of

oncology is not one of Soriot's five priorities

If Christies is so bad what

If Christies is so bad what is the world class oncology unit in Cambridge?

Site near Addenbrooks not

Site near Addenbrooks not preferred.

If you think the Christie is

If you think the Christie is world class.. then you live in a fools paradise,. this link has screwed AZ oncology

The Charnwood site was sold

The Charnwood site was sold for £1 - the rest must be worth a least a tenner of anybody's money...

Does anyone really know if or

Does anyone really know if or believe that there is anything worthwhile left to sell?

"He is restructuring to

"He is restructuring to position for a sell off, rather obvious!"

how is it obvious ?

He is restructuring to

He is restructuring to position for a sell off, rather obvious!

I have been with AZ for

I have been with AZ for sixteen years, but gave up 2 years ago and was lucky to get a job outside AZ. The big problem now for AZ R&D is that they restructure every 1-2 years. Even if every one of new reorganisations were genius (which I don’t think) they would have been destroyed by the next reorganisation before proven their possible success. In my experience the next reorganisation arrived just when you started to feel that; OK that last strategy was a very unconstructive shake up but now, a year later, we start to see how to work and it feel as we actually could find a way get efficient again. So about then BOOM the next genus’s strategy landed on top of everyone’s back.

"senior people in

"senior people in pharmaceutical companies should be paid for the new products that they deliver
But restructuring is what they do when they don't have any - it leads to less likelyhood of new products as everyone is demotivated and searching for new jobs/roles. However, it protects profits and EPS so the shareholders support it.

Restructuring is all the

Restructuring is all the rage, but it's a lot easier than actually inventing and marketing new products. Perhaps senior people in pharmaceutical companies should be paid for the new products that they deliver rather than their fruitless reorganisations. One wonders why the shareholders don't say something.

1) They are most likely nepotistic institutional shareholders
2) They can simply sell their shares indirectly

Restructuring is all the

Restructuring is all the rage, but it's a lot easier than actually inventing and marketing new products. Perhaps senior people in pharmaceutical companies should be paid for the new products that they deliver rather than their fruitless reorganisations. One wonders why the shareholders don't say something.

AstraZeneca's new strategy

AstraZeneca's new strategy gets thumbs down from S&P 08.04: S&P doesn't buy AstraZeneca CEO's revamp plan.

http://www.magic8.co.uk/ask

http://www.magic8.co.uk/ask

What/Who is the magic 8 ball?

What/Who is the magic 8 ball? Damn I wish i kept up with nicknames...

Well, the magic eight ball

Well, the magic eight ball has his ticket booked for Cambridge

How the new R&D IS will be

How the new R&D IS will be formed? From all old school boys of Rsearch Informatics VP and current RDI site leader does not talk to his own staff!

"It was a nice Silver Cross

"It was a nice Silver Cross pen and pencil at Charwood. Anyone remember "Crackerjack" on TV?"

And 1.75 times annual salary. :)

It was a nice Silver Cross

It was a nice Silver Cross pen and pencil at Charwood. Anyone remember "Crackerjack" on TV?

It's now a painting of a

It's now a painting of a Spitfire and a firm handshake.

Has the redundancy package

Has the redundancy package changed? I heard a rumour it had

That's my feeling too. I just

That's my feeling too. I just cant see Cambridge happening

Having left AZ a few years

Having left AZ a few years ago, I've lost track of the pipeline. How many compounds do AZ currently have in Phase II & III?

Never undersrood taking this

Never undersrood taking this one on, it had poor efficacy prevously but AZ insisted those were flawed studies (as usual).

Surely this is no 'news'...

Surely this is no 'news'... ok so its official now, but this mist have been on the cards for several weeks about this phase 3.

More bad news! The licensed

More bad news! The licensed Rigel cmpd for rheumatoid arthritis has failed one of the 2 primary end points in Phase 3. Also efficacy and side effect profile look inferior to Humira (a cmpd I worked on years ago when it belonged to BASF)

2nd Rate begats 2nd rate as

2nd Rate begats 2nd rate as AZ fly in smaller and smaller circles.

How long before the beak touches the bottom?

http://tinyurl.com/2ndrate

The fact that everyone in the

The fact that everyone in the industry knew AP was on borrowed time for the last 3 years and still such practices continued right to the bitter end speaks volumes about the culture there

"The selection process at AP

"The selection process at AP used to (does it still?) involve pitting candidates against each other such that the ones that best mimicked an expected artifically competitive stereotypic behaviour got the job. And you wonder why everyone was/is the same"

Nail on head.

Ex AZ here; I also predict

Ex AZ here; I also predict that no building will take place in Cambridge. My prediction is a complete withdrawal from UK R&D after AP has been run to a standstill over the next 4 to 6 years. Multiple changes of the SET followed by a resignation from PS some time in 2017 when the shit has really hit the fan. Plan your exit now you are on a very extended notice period!

"Modern labs WERE Charnwood.

"Modern labs WERE Charnwood. All still in excellent condition at closure. Nice campus feel, where projects were innovative. None of this 'oh look, another quinazoline into development' mentality. High risk/high gain approaches to R&I.
AP should have gone way before Cwd."

Sorry - Cwd was indeed better then than AP, but both had (and maybe still have?) the same sense of self-entitlement, ingrained over-bureaucratic processes, narrow thinking and more than a few crap leaders.

That being said - why is poor management always someone elses problem in this thread? If your site takes it in the shorts, it is not just "the managers fault" - it might just be your own too. Whatever level you were or are. Think about it.

I have a related theory. The selection process at AP used to (does it still?) involve pitting candidates against each other such that the ones that best mimicked an expected artifically competitive stereotypic behaviour got the job. And you wonder why everyone was/is the same?

Modern labs WERE Charnwood.

Modern labs WERE Charnwood. All still in excellent condition at closure. Nice campus feel, where projects were innovative. None of this 'oh look, another quinazoline into development' mentality. High risk/high gain approaches to R&I.
AP should have gone way before Cwd.

One reason to move to

One reason to move to Cambridge is to be near a biotech hub. However in doing this they are moving away from Christies Cancer hospital where AZ have many contacts. Hence they are moving the cancer portfolio away from one of the major UK cancer centers. Sorios says this does not matter due to modern communications ie you do not need physical proximity to work. However this argument does not work in reverse ie why move to Cambridge if communications are so easy. Instead they intend to spend 500 million on a new centre having closed both Loughborough and shortly AP. This is crazy, I predict disaster

They could move to the

They could move to the science park in Sandwich where there are modern labs up for grabs.

http://bit.ly/YSopYh Brighton

http://bit.ly/YSopYh

Brighton Pier management Consultant

"Sales of Mr Muscle will

"Sales of Mr Muscle will ........."

Oh lovely days spent with a bucket of Mr. Muscle and a mop cleaning out a fume-cupboard - first with acetone, then ethanol, then water.

Oops did I give away some AZ know-how??

So much fun - the end to a career.... no clock or retirement do.

No. Astra should move to

No. Astra should move to Milton Keynes and do what Glaxo have done, but offer labspace at competitive rates. This way they can be near oxford and cambridge.

Another alternative would be to move near colworth where there is an existing science park.

Moving to cambridge just to blend in is pointless. Just buy a couple more biotechs and work more closely with them instead of via webex.

A plot will be bought, but no

A plot will be bought, but no construction will ever take place. Expiring patents/free-falling revenue will see to that.
There will be a u-turn in the face of lost profits, and a now-idle (but interestingly still intact) site - ideally sized - will rise, phoenix-like, from the flood-plains.

... So, has the decision been

... So, has the decision been made yet on the site for the new Cambridge setup? What are the rumours?

Yes but can you get

Yes but can you get broadband?
Do you have a phone line?
Are the red cross dropping packages from above as soon as a snowflake appears.
Live out west near st neots is best but the a14 is a death trap.

"You have just proved why

"You have just proved why they are moving because you don't LISTEN because you thought you were the best of the best.Now you are joining the rest"

Who said I work/worked for AZ. Perhaps you should READ the post.

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