coming B4 year end.
i dont know why anyone tries to defend open array. sure it works but isn't supposed to be better than what is already out there...if it isnt then why bother?
OA can work, but it's not as sensitive as Real Time machines. So people get their data and compare it to RT, and then they think it is junk. It can genotype, expression i dont know.
gene expression or genotyping on the open array?
ive only done genotyping. provided I load the arrays correctly and none of my samples smear in the stupid little case they have me put the array in for cycling. the clusters are still terrible. there is no distinguishable separation. it's just one big blob sometimes. It's happened far too many times to me and when I ask LIFE about it they have no explaination for any of it.
Yes, I have used it many times. It seems to work fine. Nothing special about it for sure but it is certainly not a complete "POS" as people are writing on this forum.
The flow could be a little better, but it does what it is supposed to do with too much of a hassle.
have you used the machine? then give us your opinion about it. other than the simple comment that it works...I simply gave my experience with it. I learned the complicated workflow and even had several demonstrations given to me by LIFE, it still produced crappy data
trust me, i've used the machine and lost some very important samples. that platform simply does not work.
Why should anybody trust you? You're just another anonymous shlub on the internet complaining about something. The internet is full of people like you who do nothing but complain and spread bile all over the place.
Many people would disagree with you on this. Of course, they are busy working and using this equipment that "doesn't work" so they probably won't post up much. Even when they do - it falls on deaf ears. You can't teach the unwilling or stupid it seems.
was it data you generated and analyzed on your own from the open array? or was it presented to you by Lifers?
trust me, i've used the machine and lost some very important samples. that platform simply does not work. don't get me started about the workflow. the salesman who sold me the machine told me it would take 1 hr hands on time. yea...1 hour to load the array and then 4 hours later i find out my data is all crap.
Again what is wrong with it? Data quality? Usability? When was the last time someone sold a highthroughput instrument (in comparison with the rest of market) with proper expectations? I'm just curious as I have seen data and it's not that bad.
Of course Life is still extremely profitable and is doing quite well. The only indication that anything is "wrong" is on this site where a few idiots constantly post up rumors and BS.
In the real world - Life is doing great. Here...not so much.
Good thing we live in the real world.
Are you kidding me, the Open Array is a boat anchor, no one uses this POS except for a few folks who got one for free. It is by far one of the worst piece of junk ABI has ever made, herrr wait, they never made it, they bought it and canned the company all together... Some reps have lost major account credibility on this instrument. One PM took the empty job and fled about 10 days later, when he saw his job was basically to explain all the caveats of OA. Including the Super Array Bioscience panels they had bitched at for 2 years... hahaha what a joke of a company...
What is so bad about the open array?
solid is dead cuz the 5500's are shipping.
Solid is dead? yes, Dead just like LIFE. What a contradiction?
SOLiD: can't make money if you can't deliver. can't sell more if you can't deliver what you have sold.
SOLiD is dead. No way anyone would spend anywhere close to retail for a machine, and it's just not profitable for LIFE to give the machines away in the hope of consumable revenue.
open array FTW
SOLiD: can't make money if you can't deliver. can't sell more if you can't deliver what you have sold.
PGM: For a $50K instrument, selling 60 is good, but how many thousands need sold to even make back what Life paid for the company?
Better cut more than travel and catering to get good numbers.
iBlAMeHoWARdCaMPing. ILMN CEO is brilliant, but ILMN does not sell reagents thus limited exposure to NIH funding reduction?
don't blame the government. Blame the democrats.
"Obama cut all the government grants. LIFE is under great revenue pressure due to this fact. Q2 numbers will definitely be weak."
Don't blame the gov. ILMN is doing quite well in the same environment.
Don't go to HR especially at LIFE. These things are not human and they are there to protect the evil manager and the likes. Find another job. That what I did when I saw an email from QA threaten me before an FDA audit. I am glad to have left that hell hole.
I've received e-mails telling me I won't get paid if I don't put every little transaction in Siebel. My country manager said he could do this. I feel like going to HR because he is entering into contractual agreement beteween me and Life. This guy is a nut ! Trying to save his (fat) ass I guess.
"Travel and catering are to make Q2 numbers. All kinds of stuff must be hitting the fan for them to realize that halfway through Q2 there is going to be a big problem come the end of June. This kind of stuff usually didn't happen until the last week or so of the quarter."
Obama cut all the government grants. LIFE is under great revenue pressure due to this fact. Q2 numbers will definitely be weak.
They don't buy other companies by cutting back on travel and catering. To buy other companies, they just go in the back room and dilute shareholder value by printing up a bunch more shares, or borrowing money with the promise to pay it back in the future with newly printed shares that, again, dilute shareholder value.
Travel and catering are to make Q2 numbers. All kinds of stuff must be hitting the fan for them to realize that halfway through Q2 there is going to be a big problem come the end of June. This kind of stuff usually didn't happen until the last week or so of the quarter.
saving cash to buy pacbio.
"Life in cost cutting mode again. No travel, office supplies or catering. Serious stuff. Must be another big acquistion or layoffs in the near future."
Not true for all groups. Team Kumar can party and cater all they want.
500 Cummings Center
Beverly, MA 01915
layoffs where? has anyone heard any news? what groups? relating to SOLID?
Life in cost cutting mode again. No travel, office supplies or catering. Serious stuff. Must be another big acquistion or layoffs in the near future.
At 100K, 100 bp reads on my PGM I was able to sequence a <1X haploid genome for only $293K. Still cheaper than the human genome project.
I am sequencing whole genomes for $1500 each, whole transcriptomes for $300 each, whole exomes for $250 each.
lambda phage doesn't count as a real genome anymore.
Someone please share your insights concerning Gen-Prob. How does this fit with LIFE?
I love my PGM XL 5500 dream instrument. Follow me on twitter.
That is awesome. You should make a series of totally unoriginal and supremely stupid advertisements and post them on youtube! Marketing genius for such an outstanding experience.
I also love my SOLiD 5500 XL. The fact it doesn't exist makes my life a lot easier.
In a year LIFE will be paying you to run their instruments....oh wait, they already do.
In a year, you can do it for free. How's that.
yes, u r an idiot.
Forget Illumina and HiSeqs. Life has them beat hands down.
With my new SOLiD 5500 XL and 0.75 um beads, I am sequencing whole genomes for $1500 each, whole transcriptomes for $300 each, whole exomes for $250 each. It gets cheaper all the time do to syngergies between groups in Life Tech, allowing pricing to decrease steadily while quality increases.
In six months my Ion Torrent PGM will be doing genomes for $500 each, so I am happy that Life has stopped further development and optimization of the SOLiD I just purchased. They are such a fast moving company that the new SOLiD was already outpaced by their great new product. In six months my PGM will do $250 genomes. I cannot wait what I can do in a year, wow!
Yes. That must be it. Anyone without a bitter, defeatest attitude must be an HR troll.
Or...just throwing this out there...you must be an idiot.
May 18 (Reuters) - Bidders emerged for allergy-testing company Phadia AB and test-maker Gen-Probe Inc (GPRO.O), according to The Wall Street Journal.
Laboratory equipment company Thermo Fisher Scientific Inc (TMO.N) is a leading contender for privately owned Phadia, and is involved in the auction for Gen-Probe, the newspaper reported in its online edition.
Phadia could fetch as much as $3 billion in a sale, while Gen-Probe has a market capitalization of $3.8 billion.
Other bidders for Gen-Probe include Novartis AG (NOVN.VX), and Life Technologies Corp (LIFE.O), the newspaper said.
The companies could not be immediately reached for comment. (Reporting by Jessica Hall. Editing by Robert MacMillan) (For more M&A news and our DealZone blog, go to here)
I really have no opinion on SOLiD, having never used it. Seems that sequencing by ligation hasn't kept pace with sequencing by synthesis the last 2 years, though. My only comment was that GL (IVGN, pre-LIFE) passed on Solexa. I think that was a good thing for the scientific community, the technology ended up in much more capable hands. As a result, GL has had to make a tremendous "double-down" bet on Ion Torrent. Failure of IT to meet expectations (and I don't think the expectations are even to compete with HiSeq) will be ugly.
No he is saying Solid sucks, Solexa is good (which confomrs with my experience too) and Life tech would have ruined Solexa - almost certainly correct.
"Every time I use HiSeq data, I'm thankful that GL passed on that technology."
Really, so you would rather use SOLiD data?
someone please fire my boss, what a loser !
You must be working in Canada. I don't remember receiving so many ridiculous and terrorizing e-mails.
Big gamble on sequencing and no investment in cellular analysis. Advice to investors: sell short.
Big gamble on sequencing, lead by the man who ultimately decided Solexa would be a poor investment. Not that I'm complaining. Every time I use HiSeq data, I'm thankful that GL passed on that technology. I can only imagine what Solexa would have been "synergized" into.
they should consolidate more than that.
10/20 by Q4
I believe that qualifies as "Most". Also, some of the sites that were closed were very small and consolidated.
"most of them......I'm not sure what your point is."
BB, is that you?
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