What's going on at LIFE?

Synergies=Layoffs
coming B4 year end.

Submitted by Anonymous on

Submitted by Anonymous on Wed, 27/07/2011 - 00:01.
11/2008
"This week we witnessed a press release showcasing the Sanger Centre’s decision to remove 5 Applied Biosystems SOLiD sequencers from their laboratory. This is coming on the heels of most other centers buying more of them and may signal to other technology providers to avoid the Sanger Centre as its unlikely any relationship will be met with truly open and collaborative spirits given the history with the Sanger Centre and Solexa. At Life Technologies, we not only see the SOLiD platform expanding to 10 fold more throughput per dollar than what the Sanger Center experienced with SOLiD 2.0, we have another program in place to deliver 2-5Kb reads from real time single molecule sequencers. We are not only the largest molecular biology reagent and tool provider, we are the only provider which has DNA sequencing equipment and research programs which spans capillary electrophoresis, short read next generation sequencing (SOLiD) to single molecule real time sequencing and our relationship with your leading genomics institution is distant compared to other competitive countries like the US, Canada, Japan, Singapore, and China. I can only hope this distance is unburdened by the past history just explained as I know we can surmount any technological concerns the Sanger Centre may have and our simple presence in their lab will ensure Illumina is always providing a competitive price."

What is the point of posting this?

11/2008 "This week we

11/2008
"This week we witnessed a press release showcasing the Sanger Centre’s decision to remove 5 Applied Biosystems SOLiD sequencers from their laboratory. This is coming on the heels of most other centers buying more of them and may signal to other technology providers to avoid the Sanger Centre as its unlikely any relationship will be met with truly open and collaborative spirits given the history with the Sanger Centre and Solexa. At Life Technologies, we not only see the SOLiD platform expanding to 10 fold more throughput per dollar than what the Sanger Center experienced with SOLiD 2.0, we have another program in place to deliver 2-5Kb reads from real time single molecule sequencers. We are not only the largest molecular biology reagent and tool provider, we are the only provider which has DNA sequencing equipment and research programs which spans capillary electrophoresis, short read next generation sequencing (SOLiD) to single molecule real time sequencing and our relationship with your leading genomics institution is distant compared to other competitive countries like the US, Canada, Japan, Singapore, and China. I can only hope this distance is unburdened by the past history just explained as I know we can surmount any technological concerns the Sanger Centre may have and our simple presence in their lab will ensure Illumina is always providing a competitive price."

Whether Ion Torrent will

Whether Ion Torrent will develop commercial chips that will enable the instrument to sequence human genomes is unclear at this point. "What we have shown is that the technology has no fundamental limitations that we know of," Jain said. "From a scientific standpoint, it's a seminal paper which shows which direction things can go," he said. "How you translate that into products, and which products, is complicated and too early to speculate."

Probably on the assumption

Probably on the assumption that LIFE's Q2 will be more ugly than ILMN's Q2...

The darn LIFE stock is

The darn LIFE stock is tanking! WTF?

Even if IT worked well, are

Even if IT worked well, are there enough people out there going to buy a little sequencer and consumables that it would support the whole company? It would be like Agilent running on the bioanalyzer instrument and kit sales...

IT or die is pretty much the

IT or die is pretty much the story. If you are doing anything else you are basically going to starve.

Greg Lucifer and LIFE have

Greg Lucifer and LIFE have already become a Harvard Case study...case study! The problem with Harvard's approach is that they study failures instead of success. Lucifer fell into the Harvard abyss that was lesson planned.

PGM is already flattening.

PGM is already flattening. It's not the product, the product is OK but not great. It's just this sequencing madness that is simply just not kicking in, why, well because it's like buying millions of cell phones without any communication towers or like fighting cancer without any start. Just have a sequencer ain't gonna do very much, the data is still maddening and people still don't know what to look at , let alone handle it. It just never cease to amaze me how scientists are totally removed from actual clinical value. It's like the last Nature paper of Moore's genome, totally useless science. It's like burning food and water in front of a Somalian, it's clueless, useless. Did anyone here think it's a miracle to sequence a genome on thousands of runs of PGM ? Who cares, whats the point, they can't even tell about Moore's most basic SNP related illness.. what's the frigging point: That's why PGM will simply flatten and at 49K a pop, you better sell a shiat load to cover that 700 million $$$ and that's why Life is killing all other internal biz right now. It's a scary lousy gamble.

Every time I see a GWAS, I was to throw up.

You got it right. LT thought

You got it right. LT thought IT's PGM will sell like hot cakes. IT got 'something' but that was not ready to compete with the market. So now LT will have to make it first. Other companies will also come up with different ideas given 1 or 2 years. Apparently LT missed the present market slot. Future is future.

Either someone lied, or someone misunderstood. However, for now some people made a lot of money. We can only watch.

Does Life now lack the cash

Does Life now lack the cash to keep building by acquisition and actually have to develop a product? IT has the pressure to grow.

Fail...possibly. Displaced

Fail...possibly. Displaced with even better technology - most probably. IT is a loser in the long run. The payback just isn't there for LIFE.

IT has the full resources of

IT has the full resources of LT behind it along with the pure genius of JR. There is no way it can fail.

Ion Torrent may not be ready

Ion Torrent may not be ready now, but give it a few years and it could be the next Illumina. The first genome published with Solexa technology was also very expensive and poor quality, few years later Illumina is leading NGS. I think the only question now is the up fr...

In fact the first solexa genome was 200K so a lot cheaper than this, and it was a lot better quality to with raw read accuracy around Q27 at 30bp.

Openarray work fine if you

Openarray work fine if you follow the rules.

every product at life with

every product at life with massive resources has been a gigantic failure, too many managers, too much brown nosing and very poor execution. As they move towards the chemistry side of IT, it's gonna be wild.

Also, another thing, if there is massive IT success, the success architects will still very much live the hell of Life Tech, that is the sad part, there is no more golden years, there is no more eye of the storm. Just robots and abusive human resources. How is that for bettering human condition ?

Ion Torrent may not be ready

Ion Torrent may not be ready now, but give it a few years and it could be the next Illumina. The first genome published with Solexa technology was also very expensive and poor quality, few years later Illumina is leading NGS. I think the only question now is the up front investment in IT, was it really worth the $$ for where the technology is and where it needs to be to become competitive? Maybe Life is correct to slow down on other things and funnel resources to IT?

This company is getting

This company is getting impossible to work with.
Dont get a buffer. Just quit working with them as soon as you can!!! You have alternatives for pretty much everything. Just look for them.

Our rep told us that stocks

Our rep told us that stocks of everything are being reduced and said we should buy a buffer if we could because he didnt know how they would keep supply. Because weve known him for a while and it isnt Q end I sort of believe it could be true. Worse service ?

What other sites are seeing

What other sites are seeing layoffs?

But I thought the future was

But I thought the future was the Open Array ??? and digital PCR ???...(what are they thinking). Also selling the crap at super low prices. How can they survive ?

Because they are: Mortgaging

Because they are:
Mortgaging the future of the company
Cutting all perks
Doing horrible things to our benes (all under horrifically false pretenses)
Cutting all spending on everything BUT IT
Not investing in anything else at all (no new projects, no sustaining projects, not making anything better)

Karma baby! Enjoy whatever

Karma baby! Enjoy whatever cheat you are on...your time is coming up soon.

cheaters still laugh all the

cheaters still laugh all the way to the bank, lawsuits or not.

"But, also unfortunately,

"But, also unfortunately, SOLiD is not better than the HiSeq"...and HiSeq is also in a lawsuit as of 4 months ago.

Illumina stole their technology from a company in Washington.

No market leaders, just market cheaters!

Unfortunately SOLiD is better

Unfortunately SOLiD is better than the PGM...

But, also unfortunately, SOLiD is not better than the HiSeq. Extending read length obviously became a major issue on the SOLiD, and, especially for paired end or mate pairs, the HiSeq became the obvious choice of virtually any objective user. So you can see the business decision to look at other options...

If the MiSeq performs anywhere close to promised specs, the PGM needs 100x density and 2-3x read length improvement REAL quick.

"Unfortunately SOLiD is

"Unfortunately SOLiD is better" - and in another lawsuit as of this week.

Amin's rule was characterized

Amin's rule was characterized by human rights abuse, political repression, nepotism, corruption, and gross economic mismanagement. Sounds about right for JR.

People are negative in this forum about IT because of the resources being put towards something that is clearly not ready to make a significant impact on the next-gen market. Putting $1B into Starlight would likely have been a better choice.

Just look at the nature paper. That 10X crap human genome was easily $2M plus time and labor and 200 days of sequencing. A lab now with a HiSeq can do MUCH better for less than $7K. Do you really think you can take on Illumina with the PGM? Insanity.

We at LT see this logic and do not know why GL and his cronies do not. The PGM would have been big news years ago, but what it is now is not work the $700M++ LT is sinking into it.

If you want to argue, think about what users can buy now, cost of sequencing, how most projects are moving towards whole exomes, genomes, and transcriptomes, and how the PGM is totally useless for those three applications.

Unfortunately SOLiD is better than the PGM and LT still lost out. Way to go GL! JR must be an Illumina spy, take down LT from within.

Enjoy those nightly reports!

So who were the latest

So who were the latest victims ? Did they finally get rid of the dead wood stacked in a group called 'global account sales', seems to me, everyone who has done damage ends up there before either leaving or surviving a major demotion.

Why does GL come to Foster

Why does GL come to Foster City right after another round of layoff? Is he having a brain fart or just freaking arrogant?

How is it there seems to be

How is it there seems to be such a negative view towards IT, coming from what appear to be LT employees? One would think this would be something everyone would want to get behind and see succeed. Is the environment at LT truly this toxic?

But Roche could absorb the

But Roche could absorb the 454 failure, Life will choke on Ion.

Souds like 454 v2

Souds like 454 v2

The axe fell on several heads

The axe fell on several heads today here in FC all part of the plan to gut solid and flush more money down the torrent toilet. 700+ million was only the start, JR is happy to spend all the money GL will give, and GL's man crush on JR will keep the $ flowing.

JR's Idi Amin management style spreads like virus through the GS division, hundreds will write idiotic daily reports and send them to everyone until Life's exchange servers melt, no thought will go into anything as the flock of headless chickens run around doing more.

JR will leave with all the $ and Life will have a huge pile of shit to clean up and a giant cluster fuck business unit to deal with.

Basically more of the same.

Don't laugh at him. You can

Don't laugh at him. You can tell he's serious by the bow tie.

How many laid off today?

How many laid off today?

"One of the things [Life Tech

"One of the things [Life Tech has] done is to hire me — I'm influencing the company when opportunities arise to engage in human health applications" -Paul Billings

HAAAAAAAAAAAAAAAAAhahahahahahah

GL will never learn from his

GL will never learn from his mistakes. His initials should be GHL, H=Hubris exponential

What's going on at Life ?

What's going on at Life ? More of the same, expensive, inaccurate, marketing ploy crap. Once again I know for a fact a few folks called this one out before it was published but the minions let it slip, bravo to the academics who completely failed on this one, you crossed the line of lameness:
http://www.wired.com/wiredscience/geneticfuture

Wow, this is the story of

Wow, this is the story of hundreds of fair hard working people out there... When HR had a target, they would zone in and make anyone's life so terrible, destroying them, their pride, probably killing marriages, happiness and productivity... this my friends is what Life Tech is still much about.

This is not new. It predates

This is not new. It predates the ABI merger. Hope he wins.

Is this the Director of

Is this the Director of Molecular Biology and Chemistry Patent Groups?

http://www.leagle.com/xmlResu

http://www.leagle.com/xmlResult.aspx?xmldoc=In%20CACO%2020110714011.xml&...

Cleaning up the piles of BS

Cleaning up the piles of BS that spew out both ends of LIFE employees.

Wow, a Major Incident

Wow, a Major Incident Manager. That's incredible. What is the job description.?

From LinkedIn: ¨Life

From LinkedIn:

¨Life Technologies has a new Major Incident Manager¨

I wonder if this guy will have any spare time soon :)

Stock price < $50/sh , going

Stock price < $50/sh , going to 40s' anyone?

Bye Bye Kevin

Bye Bye Kevin McKernan

http://www.bio-itworld.com/news/07/19/2011/Sequencing-squabble-over-Ion-...

keep buying back some stock.

keep buying back some stock. I also think major cost cutting will be required again but massive enough to send a market message. Didn't we all see it coming, read the frigin thread, it's the biggest MBA nightmare case study... GL will be remembered for something, pure and utter failure to listen. Would make a great thesis subject, Hey Gregory, call me baby I have a few hints for you to turn things around.

Sparky says "why don't you

Sparky says "why don't you ask yo mama?". Don't be disrespectful to your pappa.

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