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Psychiatric advanced practice nurses (APNs) played a critical role in supporting psychological recovery after the Boston Marathon bombing - not only for injured patients, but also for family members and hospital staff, according to an article in Clinical Nurse Specialist, official journal of the the National Association of Clinical Nurse Specialists. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Brisbane's water supply has been found to contain disease carrying bugs which can be directly linked to infections in some patients, according to a new study by QUT.Dr Rachel Thomson, who has completed her PhD through QUT's Faculty of Health, said certain species of nontuberculous mycobacteria were present in Brisbane's water distribution system."We know that certain species of nontuberculous mycobacteria can cause disease and infection in humans, especially in some at-risk groups, but not all exposure to mycobacteria is harmful," she said.
In the race for better treatments and possible cures, rare diseases are often left behind. In a collaboration of researchers at The Rockefeller University, Memorial Sloan Kettering Cancer Center and the New York Genome Center (NYGC), an unusual mutation has been found that is strongly linked to one such disease: a rare liver cancer that affects teens and young adults. The results, published this week in Science, suggest that the mutation plays a key role in the development of the disease, called fibrolamellar hepatocellular carcinoma, and may also underlie more common cancers as well.
Real-time social media like Twitter could be used to track HIV incidence and drug-related behaviors with the aim of detecting and potentially preventing outbreaks, a new UCLA-led study shows.The study, published in the peer-reviewed journal Preventive Medicine, suggests it may be possible to predict sexual risk and drug use behaviors by monitoring tweets, mapping where those messages come from and linking them with data on the geographical distribution of HIV cases.
Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper published online in OncoTarget, a researcher at the University of Texas Health Science Center at San Antonio unveils the important role of microRNAs in regulating neuroblastoma development, pointing to new therapeutic possibilities.Neuroblastomas, which account for 15 percent of childhood cancer deaths, happen when some cells do not differentiate and grow as they should.
An essential weapon in the body's fight against infection has come into sharper view. Researchers at Princeton University have discovered the 3D structure of an enzyme that cuts to ribbons the genetic material of viruses and helps defend against bacteria.The discovery of the structure of this enzyme, a first-responder in the body's "innate immune system," could enable new strategies for fighting infectious agents and possibly prostate cancer and obesity. The work was published Feb. 27 in the journal Science.
Researchers from UCLA's Jonsson Comprehensive Cancer Center have developed an innovative cancer-fighting technique in which custom-designed nanoparticles carry chemotherapy drugs directly to tumor cells and release their cargo when triggered by a two-photon laser in the infrared red wavelength.The research findings by UCLA's Jeffrey Zink, a professor of chemistry and biochemistry, and Fuyu Tamanoi, a professor of microbiology, immunology and molecular genetics, and their colleagues were published online in the journal Small and will appear in a later print edition.
Three dimensional imaging of two different mouse models of Apert Syndrome shows that cranial deformation begins before birth and continues, worsening with time, according to a team of researchers who studied mice to better understand and treat the disorder in humans.Apert Syndrome is caused by mutations in FGFR2 - fibroblast growth factor receptor 2 - a gene, which usually produces a protein that functions in cell division, regulation of cell growth and maturation, formation of blood vessels, wound healing, and embryonic development.
In space, things don't always behave the way we expect them to. In the case of cancer, researchers have found that this is a good thing: some tumors seem to be much less aggressive in the microgravity environment of space compared to their behavior on Earth. This observation, reported in research published recently by the FASEB Journal, could help scientists understand the mechanism involved and develop drugs targeting tumors that don't respond to current treatments. This work is the latest in a large body of evidence on how space exploration benefits those of us on Earth.
The Wall Street Journal and Southeast Asia Realtime recently reported that: "the plantation-rich province of Riau on Indonesia's Sumatra Island has declared a state of emergency as fires set for land clearing have sent pollution levels soaring and smoke made breathing difficult for thousands."Tens of thousands of Riau residents are suffering from the effects of the smoke coming from dozens of fires set to clear land in Sumatra. Riau is the center of Indonesia's more than $20 billion palm oil industry - the world's largest.
"The results of this study are counter to most expectations," said Dr. Brachman, Director of Radiation Oncology at Barrow and St. Joseph's. "Bevacizuman had been shown in earlier studies to be an effective drug in the treatment of patients with recurrent disease. But, on newly diagnosed patients, it did not, in fact, prolong survival."The randomized, double-blind placebo controlled trial of 621 adults was funded by the National Cancer Institute and the drug manufacturer Genentech from 2009 to2012. Glioblastoma is the most common primary malignant brain tumor in adults.
A new University of Virginia psychology study has found that a sample of mostly white American children - as young as 7, and particularly by age 10 - report that black children feel less pain than white children.The study, which builds on previous research on bias among adults involving pain perception, is published in the Feb. 28 issue of the British Journal of Developmental Psychology."Our research shows that a potentially very harmful bias in adults emerges during middle childhood, and appears to develop across childhood," said the study's lead investigator, Rebecca Dore, a Ph.D.
REGiMMUNE Corporation announced that the American Journal of Transplantation (AJT) has published its paper that describes a novel approach to long-term tolerance in organ transplantation with continuous administration of immune suppressants. "A Novel Approach Inducing Transplant Tolerance by Activated Invariant Natural Killer T Cells with Costimulatory Blockade" was published in the AJT March 2014 Issue 3, Volume 14, pages 554-567, and was first made available online as an early view.
Higher education attenuates impact of TBI on cognition: results support the hypothesis of cognitive reserve in traumatic brain injury
Kessler Foundation researchers have found that higher educational attainment (a proxy of intellectual enrichment) attenuates the negative impact of traumatic brain injury (TBI) on cognitive status. The brief report was published recently in Archives of Physical Medicine & Rehabilitation. Cognitive outcomes vary post-TBI, even among individuals with comparable injuries. To examine this finding, investigators looked at whether the hypothesis of cognitive reserve helps to explain this differential cognitive impairment following TBI.
The estimated tens of thousands of Burmese pythons now populating the Everglades present a low risk to people in the park, according to a new assessment by U.S. Geological Survey and National Park Service scientists.The human risk assessment looked at five incidents that involved humans and Burmese pythons over a 10-year period in Everglades National Park. All five incidents involved pythons striking at biologists who were conducting research in flooded wetlands."Visitor and staff safety is always our highest priority at Everglades National Park," said Superintendent Dan Kimball.
Porcine reproductive and respiratory syndrome (PRRS) is the most expensive and invasive disease for pig producers on a global scale. Though it is not occurring on every farm, it is the biggest disease problem in the pig industry, said a University of Illinois animal sciences researcher.E. coli has also been a problem historically and continues to be on an industry-wide basis, said James Pettigrew. "Either disease can sweep through a farm so their alleviation would substantially reduce production costs.
Researchers at the University of Eastern Finland (UEF) have developed a novel treatment for myocardial infarction. In a study carried out at the UEF, virus vectors were used in a mouse model to deliver small RNA molecules into the heart, and this significantly reduced the size of myocardial infarction. In the novel treatment method, RNA molecules are targeted at the regulatory area of the vascular endothelial growth factor gene (VEGF-A). These molecules use epigenetic mechanisms to enhance the production of the growth factor in cells.
Endocrine disrupters are not the only worrying chemicals that ordinary consumers are exposed to in everyday life. Also nanoparticles of silver, found in e.g. dietary supplements, cosmetics and food packaging, now worry scientists. A new study from the University of Southern Denmark shows that nano-silver can penetrate our cells and cause damage.Silver has an antibacterial effect and therefore the food and cosmetic industry often coat their products with silver nanoparticles. Nano-silver can be found in e.g.
A University of Houston (UH) scientist and his team are working to develop the next generation of prostate cancer therapies, which are targeted at metabolism.With approximately one out of six American men being diagnosed and nearly a quarter of a million new cases expected this year, prostate cancer is the most common malignancy among men in the U.S. Since prostate cancer relies on androgens for growth and survival, androgen ablation therapies are the standard of care for late-stage disease.
Researchers at the Massachusetts General Hospital (MGH)/Harvard Medical School, Drs. Beste Kinikoglu and Yawei Kong, led by Dr. Eric C. Liao, cultured and characterized for the first time multipotent neural crest cells isolated from zebrafish embryos. This important study is reported in the journal Experimental Biology and Medicine. Neural crest is a unique cell population induced at the lateral border of the neural plate during embryogenesis and vertebrate development depends on these multipotent migratory cells.